Posted by: Johnson Francis on: 16 Nov, 2008
The most important beneficial effect of angiotensin converting enzyme (ACE) inhibitors is prevention of adverse cardiovascular remodeling after a myocardial infarction. Ventricular remodeling consists of infarct expansion and dilatation of rest of the ventricle. Though initially this is beneficial by increasing force of myocadial contraction and hence the cardiac output (Starlings law of the heart: [...]
Posted by: Johnson Francis on: 28 Sep, 2008
What is the role of beta blockers in heart failure? Traditionally it is thought that sympathoadrenergic system activation is compensatory in heart failure. This is true in acute heart failure. But in chronic heart failure, sympathoadrenergic system becomes counter productive and maladaptive. It increases the afterload and myocardial cell necrosis as well down regulation of [...]
Tags:
beta blocker,
cardiac resynchronizaton therapy,
Heart failure,
Hypotensive ventricular tachycardia,
ICD,
implantable cardioverter defibrillator,
Intraventricular dyssynchrony,
metoprolol succinate,
metoprolol tartarate,
Starlings law of the heart,
sudden cardiac death
