Cardiophile MD Archive

Posts Tagged ‘JLN2

Long QT syndrome (LQTS) genes

Posted by: Johnson Francis on: 06 Dec, 2008

10 LQTS genes have been described from 1991 to 2007. LQT1 gene is KCNQ1 and it encodes for alpha (KvLQT1) subunit of the potassium channel conducting the IKs current. IKs is the slow component of the delayed rectifier current, which in turn is the major repolarizing current during phase 3 of the cardiac action potential. [...]