Delayed preconditioning
Posted by: Johnson Francis on: 10 Jun, 2010
Mechanisms of chronic preconditioning include all the following except:
A. Downregulation of iNOS
B. Upregulation of COX-2
C. Opening of mitochondrial K+ATP channels
D. Involves protein synthesis
Answer: A. Downregulation of iNOS
Chronic or delayed preconditioning involves protein synthesis with upregulation of iNOS (inducible nitric oxide synthase), cyclooxygenase (COX-2) and opening of mitochondrial K+ATP channels. It can persist up to 4 days.
